Spore Forming Probiotics and Stability

Spore forming bacteria are a diverse group of very hardy bacteria, characterized by their ability to form endospores to protect themselves in varying conditions such as high temperatures and the acidic environment of the gut.

Bacillus subtilis has the ability to form spores that protect the microbes from harsh conditions until they
enter an environment ripe for germination, such as the GI tract. This means that DE111 remains viable under a wide temperature range, and doesn’t require refrigeration. It also survives passage through the acidic environment of the GI tract.

Because DE111 remains viable under a wide temperature and pH range, the probiotic is ideal for use in supplements, foods and beverages. In stability testing, DE111 experienced virtually no loss of colony forming units (CFU) over 24 months, when stored at room temperature (25°C).

DE111 can also stand up to food and beverage processing and storage.


DE111 remains stable over24 month sat 25°C and 40% relative humidity.
 

 

DE111 viability is maintained under temperatures up to 100°C for up to 5 minutes.

DE111 viability is maintained under a wide pH range for a period of three weeks.